10 Stars Who'll Be 40 in 2010

“I can’t say my thirties were the easiest time,” this actress has admitted. Fear not, Uma: In the coming decade, you’ll kick more butt than your Kill Bill character.

All hail a woman who can sing, dance, rap, act and model. This month, the Chicago star can be seen in the romantic comedy Valentine’s Day.

To the comedienne who brought us Baby Mama, Liz Lemon and a sidesplitting, Emmy-winning impression of Sarah Palin: We hope 40 rocks!

Broadway had better send its regards to this four-time Tony winner. The actress-singer, a standout in A Raisin in the Sun, now stars on Private Practice.

She’s been acting since age 11 and has grabbed attention in roles ranging from the Hulk ’s heroine to a heroin addict, nabbing an Oscar along the way.

A cross between Superwoman and Susie Homemaker, this mother of three and Live with Regis and Kelly cohost makes our heads spin—in a good way.

The 1990s supermodel is still making waves in the fashion world: Last fall, she posed topless for a British magazine. She’s expecting her third child, with her film producer husband, Matthew Vaughn, in May.

Her turn in Good Will Hunting proved she’s a larger-than-life actress, despite her little-girl name. And her performance in Circle of Friends makes us glad to welcome her to ours.

She had us hooked as the prostitute in Hustle and Flow. But it was her role as Benjamin Button’s mother, Queenie, that cemented her status as Hollywood royalty.

Tanti auguri to the Food Network’s ravishing Italian chef. In her honor, we plan to eat a heaping bowl of Everyday pasta.

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