Do this: If you are prone, take medication as soon as symptoms appear. "You stop the release of brain chemicals that cause painful swelling," explains Stephen Landy, MD, of the University of Tennessee Health Science Center. One drug, Treximet, which combines Imitrex with a painkiller, has been effective.
Or this: Consider getting needled. An Italian study of 160 patients with moderate to severe migraines found that twice-weekly acupuncture, combined with medication, was more successful at minimizing pain than either medication alone or a "sham" procedure plus drugs.