“Ultra-Bad” Cholesterol Discovered

Adults with type 2 diabetes are more likely to develop a dangerous, newly identified form of cholesterol, raising their risk of heart disease, say researchers.

By More.com Health Editors
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Photograph: Baris Onal

If you suffer from type 2 diabetes, have your heart checked. University of Warwick researchers say they have discovered an ‘ultra-bad’ cholesterol in some patients that is stickier than normal bad cholesterol—known as LDL—meaning it’s more likely to attach to the walls of arteries and form fatty plaques, which could lead to heart attacks and stroke. The study results also shed light on how a common type 2 diabetes drug, metformin, fights heart disease by blocking the transformation of normal LDL into the super-sticky LDL. "We're excited to see our research leading to a greater understanding of this type of cholesterol, which seems to contribute to heart disease in diabetics and elderly people," said lead researcher, Naila Rabbani, PhD, associate professor of experimental systems biology at Warwick Medical School. “The next challenge is to tackle this more dangerous type of cholesterol with treatments that could help neutralize its harmful effects on patients' arteries.”

Read: HealthDay

First Published May 31, 2011

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