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Shannen Doherty

Save for a 1999 interview in Star magazine, Shannen Doherty hasn’t been very vocal about her battle with Crohn’s disease, a type of inflammatory bowel disorder that can lead to abdominal pain, severe diarrhea and even malnutrition. She reportedly told the magazine, “It can kind of mess with you. There's nothing sexy about women saying: ‘I've got to go to the bathroom right now.’”

Sylvain Gaboury / PR Photos